Zero Isle Center (Japanese: ゼロのしま ちゅうおうぶZero Isle Center) is a new dungeon introduced in Pokémon Mystery Dungeon: Explorers of Sky. It is similar to Zero Isle North, in that it doesn't allow the gaining of experience or the recruiting of Pokémon. However, the Pokémon here are higher leveled and all possess 850 IQ (granting them all of their effective IQ skills) and, like Zero Isle East, only 16 items are allowed. There are two restrictions that don't appear in the other Zero Isles:
The player can't call for a rescue upon being defeated.
Hidden traps that do not affect the leader remain invisible.
Zero Isle Center is unlocked after recycling 150 times at the Spinda's Café Recycle Shop. The dungeon is 50 floors, with the last floor containing four Deluxe Boxes, each holding an Exclusive item for the team's leader, along with a Warp Zone taking the player out of the dungeon.