If held by a Kantonian Slowbro (or is present in the player's BagPE), the Slowbronite allows it to Mega Evolve into Mega Slowbro if its Trainer has a Key Stone. A Trainer can only Mega Evolve one Pokémon per battle (or only have one Mega-Evolved Pokémon at any given momentZA).
As a Mega Stone, it is unaffected by item-negating effects (such as Embargo and Klutz). Item-manipulating effects (such as Trick and Fling) cannot give or remove a Slowbronite from Slowbro.
Outside of battle
If held by a Slowbro, the Slowbronite allows it to Mega Evolve into Mega Slowbro when it performs a Spectacular Talent during a Pokémon Contest Spectacular if its Trainer has a Key Stone. Slowbro will remain a Mega Slowbro until the Talent Round ends.
One of a variety of mysterious Mega Stones. A Slowbro holding this stone will be able to Mega Evolve during battle. It won't work for a Galarian Slowbro, however.
Adds one more Mega Slowbro above the match. Actually converts the tiles directly above all other Mega Slowbro into a Mega Slowbro. This effect can replace any disruption in the tile above and counts as erasing the content of the tile for damage, but does not affect black-cloud disruptions. Does nothing if the above tile is empty.