During Mission 8: "Arezu's Predicament", Marsh Balms are able to be thrown to calm the frenzied HisuianLilligant. They are also usable in post-game rematches against her.
During Mission 15: "The Trial of Lake Valor", Marsh Balms are also used as a part of Azelf's trial in order to obtain Azelf's Fang.
Marsh Balms will leave the player's satchel upon completing the fights.