From Bulbapedia, the community-driven Pokémon encyclopedia.
Psystrike (Japanese: サイコブレイク Psycho Break) is a damage-dealing Psychic-type move introduced in Generation V. It is the signature move of Mewtwo and can be seen as a stronger version of Psyshock.
Psystrike inflicts physical damage. Despite being classified as a special move, this move calculates damage using the user's Special Attack and the opponent's Defense stat (similar to Psyshock and Secret Sword).
| The user materializes an odd psychic wave to attack the target. This attack does physical damage.
|Bold indicates a Pokémon gains STAB from this move.|
Italics indicates a Pokémon whose evolution or alternate form receives STAB from this move.
In other games
Psystrike is the only move of Mewtwo.
For Mewtwo's Final Smash, it transforms into Mega Mewtwo Y and then uses Psystrike.
In the anime
In the manga
In the movie adaptations
In other generations
In other languages