From Bulbapedia, the community-driven Pokémon encyclopedia.
Psystrike (Japanese: サイコブレイク Psycho Break) is a damage-dealing Psychic-type move introduced in Generation V. It is the signature move of Mewtwo and can be seen as a stronger version of Psyshock.
Psystrike inflicts physical damage. Despite being classified as special move, this move calculates damage using the user's Special Attack and the opponent's Defense stat (similar to Psyshock and Secret Sword).
| The user materializes an odd psychic wave to attack the target. This attack does physical damage.
|Bold indicates a Pokémon gains STAB from this move.|
Italics indicates a Pokémon whose evolution or alternate form receives STAB from this move.
In other games
Psystrike is the only move of Mewtwo.
For Mewtwo's Final Smash, it transforms into Mega Mewtwo Y and then uses Psystrike.
In the anime
In the manga
In the movie adaptations
In other generations
In other languages