Pokémon HQ Lab (Japanese: ポケモン総合研究所Pokémon Coordination Lab) is a location in Orre, northwest of most other Orre landmarks. Key NPCs are here, such as Lily, Professor Krane, and Jovi. The Purify Chamber is also located here. This is where the storyline begins in Pokémon XD, with Professor Krane being kidnapped by Cipher. It is also where the only Master Ball in the game can be obtained, given to the player by Professor Krane when the battle against Cipher reaches a turning point. This is where the player lives, in the left side of the first floor.
Trainers with a Poké Ball by their names may be challenged for a rematch after defeating certain bosses. In a rematch they may have higher-level Pokémon, and any Shadow Pokémon previously caught will be replaced.