A department store is the largest shop in a region. It can refer to:
- A store in Celadon City in Kanto, Celadon Department Store
- A store in Goldenrod City in Johto, Goldenrod Department Store
- A store in Lilycove City in Hoenn, Lilycove Department Store
- A store in Veilstone City in Sinnoh, Veilstone Department Store
- A store on Route 9 in Unova, Shopping Mall Nine
Kalos is the only region without a department store.
Game mechanic limitation with rooftops
Even though most department store rooftops are open air (the stores in Generation IV are not), and seemingly a perfect place to fly from, a player cannot use a Pokémon's Fly ability to leave the rooftop. The player's Pokémon will only fly from the ground because the rooftop has been programmed as an "indoor" location.