This is a chronological list of significant events in the anime and the episodes which they occurred in, or, for events which happened outside the series, where they happened in relation to the episodes.
Kaiser reports the existence of a Dratini in the Safari Zone. Thousands of people came to get it, which literally destroys the Safari Zone in the process. Since then, they only allow Safari Balls there. (EP035)
In the dub of EP005, Flint said Lola died at this point, rather than leaving. In subsequent episodes where Lola appears, the dub follows the original with Lola leaving home and leaving everything in Brock's care.