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Blaustein was born on October 9, 1960 in Long Island, New York, USA, as Adam John Blaustein. She was a male-to-female transexual.
In addition to being a voice actress, Blaustein was also an artist and writer. She had written and edited for Marvel Comics and, at the time of her death, was the senior digital artist at DC Comics. She created the character of Rubber-Band Man from the cartoon Static Shock. Blaustein was an artist in Tranny Road Show, a performing group composed of transgendered artists and performers. She had also collaborated with Gina Kamentsky on the cartoon Platform 6. She also coached Kayzie Rogers for anime voice acting.
It was reported on December 16, 2008 that Blaustein had passed away in her sleep on the previous Thursday after a short illness.