This section is incomplete. Please feel free to edit this section to add missing information and complete it. Reason: In which games does the Life Orb boost the damage dealt by Future Sight/Doom Desire (other than Generation VI)? Does it deal damage to the user for these moves, and when?.
Boosts the power of the holder's moves by ~30% (5324/4096), but the holder takes damage equal to 10% of its maximum HP after it uses a damaging move (rounded down, but not less than 1). Life Orb does not damage the holder if the move cannot have its power boosted by the Life Orb. It does not boost the damage for moves that deal direct damage or self-inflicted confusion damage.
The Life Orb inflicts its damage without displaying any message.
It does not cause damage to the holder when hitting a substitute. Magic Guard prevents a Pokémon from taking damage from the Life Orb.
If a Pokémon steals a Life Orb with Thief or Covet, it will take damage for the use of that move that stole the Life Orb. The Life Orb activates after the holder recovers HP with a draining move or takes damage from recoil and Rough Skin.
The Life Orb now displays a message when it inflicts damage. If a Pokémon with Sheer Force uses a move boosted by the Ability, it does not take damage from Life Orb for that move.
If a Pokémon is holding a Life Orb when Future Sight or Doom Desire that it used inflicts damage (even if it was not holding the Life Orb when it used the move), it takes damage for the Life Orb.
If a Pokémon steals a Life Orb with Magician, it will take damage for the use of that move that stole the Life Orb. The Life Orb activates before Pickpocket, so even if a Pokémon's held Life Orb is stolen by Pickpocket it still restores HP for that move. The Life Orb activates after the holder takes damage from Iron Barbs and the Rocky Helmet.