Yamaguchi began to provide voices for Pokémon starting with Whichever Way the Wind Blows as Vileplume. She then gained the role of Nurse Joy in Will the Real Oak Please Stand Up?, taking over the role from Ayako Shiraishi. She went on maternity leave from DP025-DP050, during which Kikuko Inoue filled in. While Chika Fujimura took over the role of Nurse Joy in Unova, Yamaguchi reprised the role in the Diamond & Pearl series special SS025.
- Nurse Joy (Kanto-Sinnoh: EP245-DP022; DP051-DP190; SS002-SS013; SS025; M11; The Legend of Thunder!; The Mastermind of Mirage Pokémon)
- Nico Robin/Miss All-Sunday, Nico Olvia (One Piece)
- Orochimaru, grass ninja (Naruto)
- Ritsuko Akagi (Neon Genesis Evangelion)
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