This is the Bulbapedia walkthrough for Pokémon Red and Blue Versions. This walkthrough follows the original Game Boy version, not Pokémon FireRed and LeafGreen.
The guide for those can be found here.
Celadon City
Celadon City is the second-largest city in the region, and it's got plenty going on to live up to the hype. All Trainers should be sure to visit the Celadon Department Store, since it has the best selection of any Poké Mart in the region. The Celadon Mansion is a hotel-of-sorts, and the current tenants are none other than Game Freak, the team that developed Pokémon. The Game Corner houses the slot machines, and those coins can be redeemed for valuable prizes in the Prize Corner next door. Besides all of this, Celadon is also home to the Celadon Gym, nestled on a ledge in the southwest.
Celadon Mansion
The tall building in the north of town is Celadon Mansion. Game Freak's game designer (on the third floor) promises a reward to Trainers with a completed Pokédex, and there's a new addition nearby. Leave the Mansion and follow the path behind the Poké Center, and pass through the break in the trees where you can sneak in the Mansion's back door. Take the stairs to the top floor (and have at most five party Pokémon), and inspect the Poké Ball on the table to find an Eevee. There's only one in the game, so don't miss out. Eevee is an extremely versatile creature, since it can evolve into one of three different forms. It evolves when it encounters the radiation from a Water Stone, Thunder Stone, or Fire Stone; using these stones results in either a Vaporeon, Jolteon, or a Flareon, respectively. These stones are readily available at the Dept. Store, and any of those three evolutions will make a great asset to a Trainer's team, especially since they can cover the weaknesses of the starter's final form.
Rockets again
With two Rocket grunts wandering the city, Team Rocket must have something planned for Celadon... Stop by the café in the south of town, and talk to the guy in the back corner. He lost all of his money at the slots, so he doesn't need his Coin Case anymore, and hands it over. This allows Trainers to start collecting coins for those rare prizes. Next door to the café is an operation that is shipping 2000 Pokémon a month to the Game Corner as slot prizes. Those kind of numbers mean big money, and that's got Team Rocket written all over it. They're up to something, and as one of the workers points out, it surely has nothing to do with a hidden switch behind a poster in the Game Corner.
Celadon Department Store
This is one massive department store. Talk to every clerk behind every counter to view the entire selection.
2nd floor
3rd floor
There's nothing for sale on the third floor, but talk to the clerk to get TM18 (Counter).
4th floor
The evolutionary stones are on sale here. Pick up a Water Stone, ThunderStone, or Fire Stone for your new Eevee, and grab a Poké Doll too - it may not sound like much, but it will be important in Saffron City a little later.
5th floor
Rooftop Square
Stop by the vending machines for a quick drink. Each machine dispenses Fresh Water for $200, Soda Pop for $300, and Lemonade for $350. Buy one of each to give to the little girl nearby - give her a Fresh Water for TM13 (Ice Beam), a Soda Pop for TM48 (Rock Slide), and a Lemonade to get TM49 (Tri Attack). Make sure to buy one extra drink for the Saffron City guards, and stock up on Lemonade. Like the other drinks, Lemonade can restore a Pokémon's health, but Lemonade is the most potent. It restores 80 HP, while a Super Potion only restores 50 HP.
Game Corner
All the prizes here are offered at extremely high prices, so you will need a huge supply of coins to get everything. Check the ground to find a few coins, and talk to the other gamblers to get a few more. Besides that, either buy them (50 coins for $1000) or take your chances on the slots. Some prizes (like Dratini) are extremely rare, while others (like Porygon) are one-of-a-kind.
At first glance, everything looks normal here. People are having fun at the slot machines, but there's something unsettling about the guy glaring at the poster... Approach him with a rested team.
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Trainers with a Vs. Seeker by their names, when alerted for a rematch using the item, may use higher-level Pokémon.
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The grunt runs off, leaving the poster exposed, but for now let's head to the Gym. To get there, head back to the café in the south of town, and cut down the tree blocking the way.
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Celadon Gym
CELADON CITY
POKéMON GYM
LEADER: ERIKA
The Nature Loving
Princess!
The fourth Gym. Erika's Gym is one of the easiest to defeat, since her Template:Type2s have so many weaknesses to exploit. Fire- and Template:Type2s are easiest to use here, though your own Template:Type2s are relatively immune to her attacks. For Trainers that need an extra edge, Ice Beam is a definite help here.
Celadon Gym
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Defeating the Celadon Gym earns you the Rainbow Badge, which commands all Pokémon at Lv 50 or less without question, and enables the use of Strength outside of battle (after obtaining HM04). Erika also gives out TM21 (Mega Drain), a Template:Type2 move that damages the opponent while restoring a Pokémon's health.
With the Gym defeated, it's time to infiltrate Team Rocket's Celadon operation. Examine the poster in the Game Corner, which reveals a set of stairs nearby, and descend into their hideout.
Rocket Hideout
Team Rocket's operation is headed by a shadowy figure known as Giovanni. This mob boss is in possession of the Silph Scope prototype, which can identify the ghosts back in Pokémon Tower. Track him down to recover the prototype, and force him out of the city.
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Trainers with a Vs. Seeker by their names, when alerted for a rematch using the item, may use higher-level Pokémon.
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The key to confronting Giovanni in his office is exactly that - a key. The Lift Key that operates the elevator is on the fourth floor below the Game Corner.
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Trainers with a Vs. Seeker by their names, when alerted for a rematch using the item, may use higher-level Pokémon.
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After collecting the items here, take the southern stairs up to the first floor, pick up a Hyper Potion, and fight the two Rocket grunts.
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Trainers with a Vs. Seeker by their names, when alerted for a rematch using the item, may use higher-level Pokémon.
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Backtrack to the stairs, wander through the maze again, and take the northern stairs down to the 3rd basement floor.
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Trainers with a Vs. Seeker by their names, when alerted for a rematch using the item, may use higher-level Pokémon.
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Beat the two Rocket grunts here, travel through the maze, and take the stairs in the center of the room down to the fourth floor.
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Trainers with a Vs. Seeker by their names, when alerted for a rematch using the item, may use higher-level Pokémon.
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Walk south to find an HP Up on a table. Get back to the stairs, and head north to find another grunt. Grab the TM02 (Razor Wind) from the other side of the table, and take out the Rocket. Talk to him after the battle, and he'll drop the Lift Key on the floor. Trek back to the 2nd floor, spin through the maze again, and enter the elevator to the southeast. Take it to the 4th floor, grab the Iron from the table in the southwest, beat the two guards outside Giovanni's office, and step inside to confront the mob boss.
Giovanni's guards
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Trainers with a Vs. Seeker by their names, when alerted for a rematch using the item, may use higher-level Pokémon.
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After the battle, pick up the Silph Scope that Giovanni left behind. This allows brave Trainers to identify the ghosts in Pokémon Tower. Take the elevator to the 1st floor, and beat one last Rocket on the way out.
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Trainers with a Vs. Seeker by their names, when alerted for a rematch using the item, may use higher-level Pokémon.
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Stop by the Poké Center if needed, bring along that extra drink, and walk east to Route 7. Step into the gate to get stopped right away by the guard. He automatically sniffs out the drink, and since he'll share it with the other 3 guards, Trainers are now free to come and go through Saffron City as they please. The Saffron Poké Mart offers the powerful Max Repel, and it may be a good idea to buy a few for the haunted tower. Ignore the rest of the city for now (including the Rocket grunts hanging around...), and continue east to Lavender Town.
Lavender Town
Pokémon Tower
The Template:Type2s here are totally immune to Normal and Fighting moves, so avoid bringing Pokémon that rely on those attack types. Anything that can dig, and anything with a strong Template:Type2 attack, like Kadabra or Drowzee, are good choices to bring along. To avoid the random encounters, just spray on the Max Repel (but don't forget to catch a Gastly).
Rival battle #5 (2F):
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Trainers with a Vs. Seeker by their names, when alerted for a rematch using the item, may use higher-level Pokémon.
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4F
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Trainers with a Vs. Seeker by their names, when alerted for a rematch using the item, may use higher-level Pokémon.
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5F
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Trainers with a Vs. Seeker by their names, when alerted for a rematch using the item, may use higher-level Pokémon.
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There is a Channeler in the middle of the 5th floor that hasn't been possessed, and she maintains a healing area with her white magic. This protected zone will heal all of a Trainer's Pokémon, restoring health and eliminating any status problems.
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Trainers with a Vs. Seeker by their names, when alerted for a rematch using the item, may use higher-level Pokémon.
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As you approach the stairs leading to the top floor, the true ghost attacks. The Silph Scope activates, revealing a level 30 Marowak. This may look like a great addition to the Pokédex, but this spirit can't be caught, so all you can do is defeat it. Once the battle is over, the mother Marowak's spirit is calmed, and departs to the afterlife, finally able to rest in peace. Take the stairs to the top floor, right into a group of Rockets.
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Trainers with a Vs. Seeker by their names, when alerted for a rematch using the item, may use higher-level Pokémon.
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After the grunts run off, talk to Mr. Fuji to wind up at his home at the foot of the tower.
Mr. Fuji's house
Speak with him again to get the Poké Flute, an item that instantly awakens any sleeping Pokémon. It also awakens the Snorlax near Celadon City, and the Snorlax south of Lavender Town.
Now head back to Saffron City.